π Lupi (Latinised to Pi Lupi) is a multiple star system in the southern constellation Lupus.

Two components form a wide binary pair with an orbital period of 517 years and a semimajor axis of 1.59″.

They belong to the Upper Centaurus Lupus component of the Sco–Cen complex.

The eclipses are shallow, with the brightness dropping by only 1% or about 0.01 magnitudes.

[1] π Lupi A (HR 5605, HD 133242) has been classified as a spectroscopic binary by at least two studies,[7][8] but both components may be spectroscopic binaries.