16, is a chamber music composition by the Romanian composer George Enescu, written in 1909 and first performed in Paris the same year.

[7] The main theme is particularly expressive, with modal coloring, and is presented at the outset of the movement in the cello.

[2] The second theme group is largely derived from the first theme, but displays a scalewise melodic cell alternating semitones and whole tones, which will emerge as a full descending octatonic scale five bars after rehearsal 39.

In the coda, the piano unexpectedly introduces the secondary theme of the first movement, which is the only cyclic feature found in this work.

[9] It possesses a relentless rhythmic pulsation which, together with a vigorous cheerfulness, serves well the traditional function of a finale, but also that of a scherzo, a movement this work lacks.