Picacho (/piːkɑːtʃoʊ/) is an unincorporated community and census-designated place in Pinal County, Arizona, United States.

Picacho is located near Interstate 10, 4.5 miles (7.2 km) southeast of Eloy and 7 miles (11 km) northwest of Picacho Peak State Park.

Picacho has a post office with ZIP code 85241, which opened in 1881.

[2] The community's name is Spanish for "peak" and is derived from the Picacho Mountains.

[4] By late 2012, parts of Picacho were to be removed under Arizona eminent domain law on account of Interstate 10 expansion.