Pickensville is a rural town in Pickens County, Alabama, United States.

As of the 2020 United States census, there were 557 people, 309 households, and 198 families residing in the town.

24.3% of all households were made up of individuals, and 7.5% had someone living alone who was 65 years of age or older.

The Tom Bevill Visitors Center and Museum is a replica of an antebellum plantation mansion built on the Tombigbee River.

It houses exhibits on the Tennessee-Tombigbee Waterway and was named for Tom Bevill, a former U.S. Representative from Alabama who chaired the congressional committee that approved funding for the waterway project.

[9] Below are photographs taken in Pickensville in April 1937 as part of the Historic American Buildings Survey (HABS) during the Great Depression: