[1] The settlement is located at the intersection of County Roads 28 and 29 in northern Monroe Township.

Variant names of Pickrelltown include "Frogtown", "Pickereltown", "Pickeretown", and "Pickreltown".

[2] The community was named for Henry Pickerel, the proprietor of a local tanyard.

[3] Pickrelltown is a short distance south of Mad River Mountain Ski Resort and southeast of Bellefontaine.

The headwaters of the Macochee Creek, a small stream that meets the Mad River at West Liberty, are located around Pickrelltown.