In 1129 Pickwell and Leesthorpe were held by Roger de Mowbray (Lord of Montbray) who had acquired all Geoffrey's land in Leicestershire.

After the death of John de Mowbray, 4th Duke of Norfolk, in 1476, and of his daughter and heir Anne in 1481, the Mowbray estates were divided between the representatives of her two co-heirs, one of whom, William, Lord Berkeley, obtained the overlordship of Pickwell and Leesthorpe for considerable time for his family: last mentioned in connection with Pickwell and Leesthorpe in 1630.

and le Brabazon, and by 1346 William Curzon whose family thereafter appears as the only considerable landowners at Pickwell itself and the family continued to hold the manor which appears to be the main estate, until 1532, when Thomas Curzon sold his lands in the parish, then described as the manors of Pickwell and Leesthorpe, to Richard Cave.

From her the lands, generally described subsequently simply as the manor of Pickwell, passed to her descendants, the Noel family, Earls of Gainsborough who were still in possession in 1936.

Later owners appear to have ceded much land with John Suffield Brown, Ayscough Smith and Rev.