Picornavirales is an order of viruses with vertebrate, invertebrate, protist and plant hosts.

[2] First, picorna- is an acronym for poliovirus, insensitivity to ether, coxsackievirus, orphan virus, rhinovirus, and ribonucleic acid.

[2] Secondly, pico-, meaning extremely small, combines with RNA to describe these very small RNA viruses.

[2] The order comprises viruses that historically are referred to as picorna-like viruses.

The families within this order share a number of common features: The evolution of picorna-like viruses seems to have antedated the separation of eukaryotes into the extant crown groups.