Piergiorgio Bertoldi (born 26 July 1963) is a Catholic archbishop and Apostolic Nuncio of the Holy See.

He received his priestly ordination by cardinal Carlo Maria Martini on 11 June 1988 for the Archdiocese of Milan.

He attended the Pontifical Ecclesiastical Academy and entered the diplomatic service of the Holy See.

He then worked for the diplomatic missions of the Holy See in Uganda, Republic of Congo, Colombia, the former Yugoslavia, Romania, Iran and Brazil.

On 24 April 2015 Pope Francis appointed him titular archbishop of Spello and apostolic nuncio to Burkina Faso and Niger.