[2] After his football career ended due to a knee injury, Dusio started a textile business which expanded into manufacturing sport equipment and supplying military uniforms.

In 1936 he established the Scuderia Torino and took part in the 1936 Italian Grand Prix at the wheel of a Maserati 6C-34, finishing sixth behind Bernd Rosemeyer, Tazio Nuvolari, Ernst von Delius, René Dreyfus and Carlo Pintacuda.

He commissioned Dante Giacosa of Fiat to develop a racing car and founded the "Consorzio Industriale Sportiva Italia", later known as Cisitalia.

[5] Dusio continued financing his racing car projects, but the expenses in engineering the complex 202MM[6] almost bankrupted Cisitalia in 1947.

Dusio tried to qualify for one Formula One World Championship Grand Prix (Italy 1952) with a Cisitalia D46, but failed to set a time in practice due to engine problems.