Pierpaolo De Negri (born 5 June 1986) is an Italian professional road bicycle racer, who most recently rode for UCI Continental team MsTina–Focus.

[2] During his career, De Negri has also served a doping suspension, after testing positive for anabolic–androgenic steroids (AAS).

In July 2012, De Negri took his first victory for the team, by winning the Trofeo Matteotti race in Italy in a sprint of 25 riders.

[2] On 21 December 2017, De Negri tested positive for anabolic androgenic steroids.

[6] In November 2019, De Negri was given a four-year ban – backdated to February 2018, when the positive test was announced.