[2] Born at La Salvetat de Blanquefort, near Agen, he had a classical education, and then went to Paris.

[1] His major work was his Cours entier de philosophie ou Système général selon les principles de Descartes (3 vols., Paris, 1690), where he presented in a systematic way the principles of Cartesian philosophy.

Opposed to Malebranche's idealism, against which he wrote in the Journal des Savants (1693 and 1694), Régis modified the system of Descartes on various points in the direction of empiricism.

[1] The Cours was criticized by Pierre Daniel Huet and the Parisian Professor Jean Duhamel.

Régis then wrote Réponse au livre qui a pour titre Censura philosophiæ Cartesianæ (Paris, 1691), and Réponse aux reflexions critique de M. Duhamel sur le système cartésian de M. Régis (Paris, 1692).