Piki Mach'ay (Quechua piki flea, mach'ay cave,[1][2] "flea cave", also spelled Pikimachay, Piquimachay, where machay means "drunkenness", "to get drunk" or "a spindle packed with thread")[1][2] is an archaeological site in the Ayacucho Valley of Peru.

[6] Artifacts discovered in the site include unifacial chipped tools, such as basalt and chert tools, choppers, and projectile points, and bone artifacts of horses, camelids (Camelidae), giant sloths (Megatherium) dating from 15,000 to 11,000 years BCE.

[6][7][8] Piki Mach'ay yielded some of the oldest plant remains in Peru, including an 11,000-year-old bottle gourd.

[5] Strata from later periods at the site revealed fishtail point arrows, manos, and metates.

By 4,000 years BCE corn (Zea mays) and common beans were grown.