[2] By 2014 the IDEO incubated company was licensed in 31 states and shipping medication in dosage packets with robots handling the packaging process.

[3] Software development and management were based in Somerville, Massachusetts, with pharmacy fulfillment operations at the Millyard complex in Manchester, New Hampshire, former site of the Amoskeag Manufacturing Company.

PillPack launched the website FixPharmacy.com and began a publicity campaign, urging affected customers (which represented about a third of its business) to complain to Express Scripts.

[8][9] In June 2019, the federal district court for Rhode Island ruled that former CVS Caremark head John Levin violated his 18-month non-compete agreement by working at PillPack in a position responsible for insurance payment negotiations.

[12][13][14] In May 2022, PillPack agreed to pay $5.79 million to the federal government and some states settle a Department of Justice lawsuit.