Littleton/Route 495 station opened several miles away in 1980 as an inexpensive park-and-ride to gather commuters from the northwest Boston suburbs.

In 2011, work began on the construction of a new station, with a full-length handicapped accessible platform and a pedestrian bridge to the parking lot, as part of a larger project to improve the Fitchburg Line.

[4] The long building included separate rooms for passengers and freight, and a living area for the station master.

[3]: 130 Residents were not allowed to ride trains on Sundays until 1850, and for some time thereafter only for the purpose of attending religious services.

[3]: 143  Despite minor accidents in 1845 and 1849, and a crash of the Tunnel Express on October 7, 1880, which killed two passengers, the railroad became important to daily life in Littleton.

Fifteen cars on a B&M freight derailed at Littleton on May 27, 1956, injuring one resident and blocking the main line for days.

After subsidy arrangements were made with several towns, service was partially extended back to Ayer – including the Littleton stop – on June 28, 1965.

The building was occupied for a time by McElroy Manfucturing Corporation (a telegraph producer) then later that year by Learning Things (an educational product developer).

Littleton, with just 21 daily commuters, refused to pay its $12,300 bill in 1974; Ayer also failed to reach an agreement.

[6][9] On December 27, 1976, the MBTA bought the B&M's northside commuter rail assets, including the entire length of the Fitchburg Line.

A new station, Littleton/Route 495, opened some 1.6 miles (2.6 km) to the southeast, using spare parking lots from an adjacent industrial firm.

[12][13] In 1995, local officials proposed building a new station with dedicated highway ramps off Route 2 to the southeast, as the Foster Street site was considered too rural for a garage or large lot.

[19][20] The additional parking proved so popular that in 2014, Littleton town officials considered the construction of a 200-space garage.

[23] In April 2017, the MBTA announced $1.5 million in funding to expand parking at the station, with between 43 and 109 additional spaces.

North Littleton station was located on the 1858-opened Stony Brook Railroad at Great Road (Route 119).

[2] The Fitchburg Railroad also stopped at Boxboro station at Depot Road, just south of the Littleton town line.