The seeds are ovule in shape, being 0.2 and 0.24 in length, and have an angled tip colored a pale brown.

[13] The species name serotina is derived from the persistently serotinous cones that may remain closed for several years before they release their seeds.

[4][15] Pinus serotina is primarily found in wet and poorly drained sites, most commonly in or near swamps, ponds, bays, marshes, and pocosins.

[18] Pinus serotina is commonly found in wet and poorly drained sites, but it will grow very well in mineral soils.

[22] Pinus serotina stands provide habitat and support for many wildlife species, particularly for birds and mammals in wetlands and flatland environments.

[23] In order for reproduction to occur, Pinus serotina needs fire in the form of intense scorching or defoliation.

When parts of the tree are top killed by fire, epicortical buds can resume growth.

Without the heat from a fire the seed fall is limited by the serotinous cones of pond pine.

Pond pine seedling growth is often limited by the moisture in the soil, lack of nutrients, and competition.

[25] It is suggested that Pinus serotina might be a valuable remedy to treat the kidney, and can be administered as a rub or in a steam bath.

[26] These trees also face the eastern pine weevil and are susceptible to wind damage.