In 1450 Alberto II Pio (1418–1463) obtained from the house of Savoy, for himself, his brothers and their descendants, the privilege of adding the style "di Savoia" to their surname, as a reward for his military services.
Another branch of the family, called "Giberto line" after one of Albert II's brothers, renounced in 1499 the coregency over the lordship of Carpi in favour of Ercole I d'Este, Duke of Ferrara, and accepted in exchange the Este fief of Sassuolo.
Carlo's half-brother Giberto Pio (ca 1637–1676), who had inherited the principality, soon moved to Spain, where, through his marriage to Juana de Moura Corte Real y Moncada (mid 17th century–1717), he also acquired for his descendants the merely nominal marquis title of Castelo Rodrigo, and the effective one of the Dukedom of Nocera (referring to the locality of Nocera de' Pagani in the Kingdom of Naples at the time under Spain).
In 1720, the title of Grandee was conferred upon his son Francisco Pío de Saboya y Moura, erstwhile Governor of Madrid and Captain General of Catalonia.
[2] In 1930 the King of Italy Victor Emmanuel III of Savoy again bestowed upon Don Manfredo, head of the Galasso family line, the title of Prince Pio di Savoia.