With Danish international Klaus Berggreen among their stars, Pisa managed a credible 11th place in the 1982–83 Serie A with 27 points and 27 goals scored and conceded in 30 games.

The following season brought relegation (during which they recorded just 3 wins and 16 draws) with 15,000 fans travelling to Milan for the fateful penultimate game.

The last promotion to Serie A was achieved in 1990, and with the talents of players like Maurizio Neri, Michele Padovano and Lamberto Piovanelli up front and Diego Simeone, Henrik Larsen and Aldo Dolcetti in midfield, the side started well and was briefly atop the standings, only to suffer another relegation.

[5] In 2005–06, the team, initially thought to be a protagonist for the promotion, were in continuous struggles, and avoided relegation after playoffs in two dramatic regional derbies against Massese.

For the 2007–08 Serie B campaign, the first in 13 years, Gian Piero Ventura was named to replace Braglia at the helm of the nerazzurri.

Despite initial predictions of a mid-low table place, Pisa's impressive performances brought the team to fight for a direct promotion spot, also thanks to a forward line composed by Alessio Cerci, José Ignacio Castillo and Vitali Kutuzov which proved to be among the finest in the league.

The club ended the regular season in sixth place, therefore achieving a spot to the promotion playoffs, where Pisa was later defeated by Lecce.

In 2008–09, the club was acquired by Rome entrepreneur Luca Pomponi, who initially failed into appointing Alessandro Costacurta as new head coach, thus confirming Ventura as nerazzurri boss.

The appointment of Bruno Giordano, which was made to improve the team results, however proved to be disappointing in terms of results, as Pisa slowly lost positions in the table, and shockingly got directly relegated in the final game of the season due to an injury-time home defeat to Brescia which left the Tuscans in 18th place.

[6] The team was then admitted to Lega Pro Prima Divisione for the 2010–11 season to fill vacancies created by a row of club exclusions in second and third tier of Italian football league system.