The film series features an ensemble cast, including Anna Kendrick, Rebel Wilson, Anna Camp, Brittany Snow, Skylar Astin, Adam DeVine, Ben Platt, Alexis Knapp, Hana Mae Lee, Ester Dean, Hailee Steinfeld, Chrissie Fit, John Michael Higgins, and Banks; while the television series stars DeVine.

With new members, tough competition, and doubts everywhere from almost everyone, they try to regain their glory, only to find it harder than it looks with their focus being split up and losing their harmony along the way.

[1] In March 2022, Sarah Hyland, Jameela Jamil, and Lera Abova were announced to be joining the cast alongside Flula Borg, who is reprising his role as Piëter Krämer from the second film.

[2] The film is based on Mickey Rapkin's non-fiction book Pitch Perfect: The Quest for Collegiate a Cappella Glory.

Rapkin, senior editor at GQ magazine, spent a season covering competitive collegiate a cappella.

According to producer Elizabeth Banks, "The character Beca required someone who was grounded, who has a strong point of view on the world, who is funny and empathetic and someone who we can all relate to and root for."

"[4] Rebel Wilson was recognized for her performance in the comedy film Bridesmaids upon auditioning for the role of Fat Amy, which she won instantly.

Moore recalled Wilson singing Lady Gaga's "The Edge of Glory" while beating "on her chest with her fists."

Banks said that she and her husband are "big Workaholics fans," and after watching one night during the film's casting, they saw DeVine and "immediately thought" he would be a good choice for Bumper.

"[4] Kelley Jakle was brought in as a "ringer" due to her past experience as a two-time ICCA champion with the SoCal VoCals and had also appeared on two seasons of The Sing-Off.