Other sports have won a variety of conference titles, regularly compete in NCAA championship events and have produced a plethora of professional and Olympic athletes.

In addition, ESPN.com used the Sagarin mathematical system to rate universities based on the strength of their performance in football and men's basketball for five years through 2006 and found Pitt was tied for 10th as one of the nation's top two-sport schools.

[20] The baseball team was ranked in the top 25 during several of the past seasons and moved into a new facility, the Charles L. Cost Field at the Petersen Sports Complex, in 2011.

National Championships (2 Helms): 1927–28, 1929–30 (23–2) NCAA Final Four (1): 1941; Elite Eight (3): 1941, 1974, 2009; Sweet Sixteen (7): 1957, 1974, 2002, 2003, 2004, 2007, 2009 NCAA tournament appearances (27): 1941, 1957, 1958, 1963, 1974, 1981, 1982, 1985, 1987, 1988, 1989, 1991, 1993, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2013, 2014, 2016, 2023 NIT appearances (9): 1964, 1975, 1980, 1984, 1986, 1992, 1997, 2001, 2015 Conference Championships: Tournament (4): 1981, 1982, 2003, 2008; Regular Season (10): 1933, 1934, 1935, 1937, 1987, 1988, 2002, 2003, 2004, 2011 The Pittsburgh Panthers women's varsity basketball program started during the 1914–1915 school year and lasted until 1927 before going on hiatus until 1970.

Pitt women's basketball plays its home games at the Petersen Events Center and is coached by Lance White.

NCAA Sweet Sixteen (2): 2008, 2009 NCAA tournament appearances (4): 2007, 2008, 2009, 2015 NWIT/WNIT appearances (5): 1981, 1994, 2000, 2006, 2010 Conference Championships: Regular Season (1): 1984 Men's and women's cross country at Pitt host home meets at adjacent Schenley Park and is overseen by head coach Alonzo Webb with distance assistant Adam Bray.

[26] Some of football's all-time greatest coaches and players have plied their trade at Pitt, including Pop Warner, Jock Sutherland, Marshall Goldberg, Joe Schmidt, Mike Ditka, Tony Dorsett, Hugh Green, Mark May, Dan Marino, Bill Fralic, Curtis Martin, Larry Fitzgerald, Darrelle Revis, Aaron Donald, and LeSean McCoy.

Among the top schools in terms of all-time wins,[27] Pitt teams have claimed nine national championships[28] and boast 87 players that have been chosen as first-team All-Americans.

Pitt football plays its home games at Acrisure Stadium and has practice facilities located at the UPMC Sports Performance Complex.

NCAA runner-up (2): 1954, 1957; Top Ten finishes (13): 1952, 1953, 1954, 1955, 1956, 1957, 1958, 1959, 1960, 1961, 1962, 1963, 1970 NCAA championship appearances, team scored (68): 1952, 1953, 1954, 1955, 1956, 1957, 1958, 1959, 1960, 1961, 1962, 1963, 1964, 1965, 1966, 1968, 1969, 1970, 1971, 1972, 1973, 1974, 1975, 1976, 1977, 1978, 1979, 1982, 1983, 1984, 1985, 1986, 1987, 1988, 1989, 1990, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2021, 2022, 2023 Individual National Champions: 17 Conference Champions: Tournament (6): 1954, 1955, 1956, 1960, 2011, 2012, 2013; Regular Season (5): 2010, 2011, 2012, 2014, 2023 University-sponsored varsity sports that no longer exist at Pitt included men's teams in boxing, fencing, golf, ice hockey, gymnastics, rifle, tennis, volleyball (1979–1983), and water polo; as well as women's field hockey and tennis.

[42][43] At the 2007 NCA/NDA Collegiate Cheerleading and Dance National Championships, Pitt's Cheer squad won the 2007 Challenge Cup and finished in eighth place overall in the All-Girl Division I category.

The Panthers play their home games at Turner Valley Fields in Norwin PA,[88] Pitt has contributed to the growing popularity of rugby in Western Pennsylvania.

Pitt Previously competed in the College Hockey Mid-America (CHMA) where it won the conference tournament in 2016 and regular season titles in 2017, 2018, 2020, and 2022.

Although the two teams ended play for years due to long-standing coaching and administrative feuding, the rivalry remained heated among some fans.

Pitt's biggest rivalry in recent years has been with West Virginia University, which began with football games that date back to 1895, and spills across multiple sports.

The rivalry had been relatively unique in college athletics in recent years as the two most high-profile sports, football and men's basketball, have resulted in games between teams have been all been nationally ranked in the same season.

However, the football and basketball rivalries between the two schools were on hiatus due to Pitt and West Virginia moving into the ACC and Big 12 conferences, respectively.

A four-year home and road football series has been scheduled from 2022–25, with Pitt winning in 2022, 38-31, in front of the largest crowd ever to attend a Pittsburgh sports function (70,622).

The series currently scheduled to be held every year at PPG Paints Arena and attracts significant local interest.

In other sports, Pitt and Notre Dame both competed against each other regularly as members of the Big East Conference and those competitions continued when both schools moved into the ACC.

Pitt and Syracuse have played in football without interruption since 1955, a streak that will continue when both schools move into the ACC and become designated cross-division rivals in that conference.

This annual Big East Conference game stems from both cities being situated along the Ohio River and features a trophy of a riverboat telegraph (a device for signaling the boat's engine room).

In the 2008–2009 season, Pitt earned its first win over the country's top-rated team by beating UConn on the road, and later at home while Connecticut was again ranked #1.

Beginning in the 1980s, Pitt had an intense basketball rivalry with cross-state school and fellow Big East Conference member Villanova that was touched off by recruiting battles over several high-profile players.

From 1935 to 1941 Pitt football had a notable series with Fordham University which was then coached by Jim Crowley and featured guard Vince Lombardi.

The series received attention because, at the time, both schools were national football powers whose first three meetings resulted in scoreless ties (1935, 1936 & 1937).

[102] In addition, a costumed mascot, named "Roc", performs with the Pitt Cheerleaders at various athletic and non-athletic university events.

The student section for basketball, the "Oakland Zoo", has received national acclaim for the atmosphere it helps to create in the Petersen Events Center.

There have been many notable individuals who have been associated with the University of Pittsburgh throughout its history ranging from athletes like Mike Ditka and Larry Fitzgerald, to celebrities like Gene Kelly and Fred Rogers, writers like Michael Chabon, businessmen like Andrew Mellon, and scientists like Jonas Salk.

Starting with the 2010–11 school year Comcast and Xfinity in Western Pennsylvania will receive an all-Pitt-Panthers network featuring all sports and commentary hosted by Pitt in second-tier cable packages.