The municipality of Plüderhausen lies in the Rems Valley, nestled between the heights of the Schurwald and the Welzheimer Forest at an elevation ranging between 260 and 505 m, with the town center at 274 m. The municipality of Plüderhausen is bordered to the north by Welzheim, to the east by Waldhausen (Lorch), to the southeast by Börtlingen, to the south by Adelberg, to the west by Schorndorf, and to the northwest by Urbach.

[5] A narrow wedge of the Urbach district, which extends northeast to the Walkersbach valley, divides the municipality of Plüderhausen into a larger southern part around Plüderhausen village and a smaller northern part around Walkersbach village.

In the earliest known documentary record from 1142, Plüderhausen was referred to as "Pliderhusen," a name derived from the Old High German blidheri, which roughly means "happy army.

[8] In 1519 Jörg Staufer, a member of the Swabian League, burned down the Plüderhausen church and 80 homes during a military campaign against Duke Ulrich of Württemberg.

As Prince Elector John Frederick of Saxony initiated his retreat in 1546 after defeat in the Schmalkaldic War, he and his army spent the night of 27–28 November in Plüderhausen, prompting complaints by the Obervogt of Schorndorf about the bad behavior of the robbing and plundering troops.

[7] The Cannstatt–Wasseralfingen branch of the Rems Railway provided Plüderhausen with a rail connection in 1861, leading to growing industrialization.

[9] Plüderhausen was not damaged in World War II, and was surrendered to the United States Army on 20 April 1945 without a struggle.