Plasmin-α2-antiplasmin complex (PAP) is a 1:1 irreversibly formed inactive complex of the enzyme plasmin and its inhibitor α2-antiplasmin.
[5][6] PAP levels are increased with pregnancy[7] and by ethinylestradiol-containing combined birth control pills.
[5] Conversely, levels of PAP do not appear to be affected with menopausal hormone therapy.
[6] PAP levels have been reported to be elevated in men with prostate cancer.
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