Playing Mona Lisa is a 2000 American comedy film directed by Matthew Huffman and starring Alicia Witt, Harvey Fierstein, Johnny Galecki, Elliott Gould, Marlo Thomas, Molly Hagan, and Brooke Langton.

Claire is forced to move home with her parents (Marlo Thomas, Elliott Gould), where sister Jenine (Molly Hagan) is busy planning a wedding.

Claire's mom is into the occult, her teacher (Harvey Fierstein) tries to arrange auditions and friends try to hook her up with a new romantic prospect, Eddie, adding to the complications in her life.

The cast shamelessly overplays their nitwit roles for laughs, which are rarely present, and the underlying idiocy of the various plotline twists becomes so irritating that one wishes mobsters from a Scorsese film could stop by to shoot off a few kneecaps.

"[10] Buzz McClain of AllMovie gave the film a two out of five-star rating, noting: "A lighter touch for this would-be screwball comedy was called for than what director Matthew Huffman gives it.