It is about six young people and a seven-year-old boy who share common dreams about their past lives as alien scientists who observed the Earth from the Moon.

The story centers around high-school student Alice Sakaguchi, her seven-year-old next door neighbor, Rin Kobayashi who attends elementary school, and five other students who have recurring collective dreams about a group of alien scientists stationed on the Moon observing and collecting data about the Earth.

[3] The character design of Issei's sister Kyoko was influenced by Osamu Tezuka and is a homage to classic style of manga artists such as Miyako Maki, Makoto Takahashi, Hideko Mizuno, and Shotaro Ishinomori.

[4] Written and illustrated by Saki Hiwatari, Please Save My Earth was serialized by Hakusensha in the monthly magazine Hana to Yume from December 20, 1986 to May 20, 1994, with its chapters collected in 21 tankōbon volumes.

[11] Please Save My Earth was adapted as an original video animation (OVA) directed by Kazuo Yamazaki and produced by Production I.G.

[12] Please Save My Earth – Special Omnibus Edition: From Alice to Rin (ぼくの地球を守って 総集編完全版 〜亜梨子から、輪くんへ〜, Boku no Chikyū o Mamotte Sōshūhen Kanzenban Arisu kara, Rin-kun e) is a 100-minute compilation movie narrated by Alice, reminiscing on the events of the main OVA as she is on her way to meet with Rin in a park.

[15] Several manga artists have cited Please Save My Earth as an influence on them, including Naoko Takeuchi and Bisco Hatori.

[16] Jason Thompson called Please Save My Earth in Manga: The Complete Guide a "masterpiece of young-adult science fiction" and praised Hiwatari's "slow-paced" as well as "consistently rewarding and unpredictable" storytelling.