[3] The current morphology and previous tectonic activities of the area have produced several endemic plant and animal species due to allopatric speciation.
[3] Two ponds in Los Linderos, Sierra de Comechingones had a total of 13 individuals of the species.
[4] Typical habitat is represented by temporary and semi-permanent ponds, at the high grassland, with vegetation at the edges and a depth of 20 to 30 cm.
[6] Pleurodema cordobae adults are relatively small in size and possess short snouts.
[5] This resemblance to the true eyes is the reason behind the common name “four-eyed frogs” for the Pleurodema genus.
[5] There is also a bright red-orange patch found on the frog's groin surrounding the lumbar glands.
[4] The oral disc of the tadpoles is anteroventral and laterally emarginated with either a single alternated or double row of marginal papillae.
[4] The spiracle tube of the P. cordobae tadpole is single, short, sinistral, lateral, and posterodorsally directed.
[4] Pleurodema cordobae tend to be similar in reproductive habits to P. kriegi and P. bibroni species, in that the males use a call to mate with the females.
Its range overlaps with Pampa de Achala Provincial Water Reserve and might extend into the Quebrada del Condorito National Park.