Cities and towns are marked in bold: Dýšina - Chrást - Chválenice - Kyšice - Letkov - Lhůta - Losiná - Mokrouše - Nezbavětice - Nezvěstice - Plzeň - Starý Plzenec - Šťáhlavy - Štěnovický Borek - Tymákov The terrain goes from slightly undulating in the west to hilly in the east.

The territory extends into two geomorphological mesoregions: Švihov Highlands (southeast) and Plasy Uplands (northwest).

[1] Four significant rivers flow into the district: Mže, Radbuza, Úhlava and Úslava.

Their confluence in Plzeň forms the Berounka River, which flows along the district border further to the northeast.

The largest of these companies with at least 1,000 employees are:[5] The D5 motorway (part of the European route E50) from Prague to Plzeň and the Czech-German border passes through the district.