Poecilanthrax is a large, primarily Nearctic genus of flies belonging to the family Bombyliidae.

They have large elongate pictured wings, with 2 or 3 submarginal cells and no vein M2.

The abdomen is moderately lengthened, with 7 visible tergites.

The front tarsi are reduced, and the tibia smooth.

[1] Data sources: i = ITIS,[4] c = Catalogue of Life,[5] g = GBIF,[6] b = Bugguide.net[7]