Pognana Lario (Comasco: Pugnana [puˈɲana]) is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about 45 kilometres (28 mi) north of Milan and about 9 kilometres (6 mi) northeast of Como.

Pognana Lario borders the following municipalities: Faggeto Lario, Laglio, Nesso.

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