Poinson-lès-Grancey (French pronunciation: [pwɛ̃sɔ̃ lɛ ɡʁɑ̃sɛ], literally Poinson near Grancey) is a commune in the Haute-Marne department in north-eastern France.

The Ource flows northeastward through the southern part of the commune, then forms its north-eastern border.

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