Pointe-à-la-Croix (French pronunciation: [pwɛ̃t a la kʁwa]; Cross Point in English) is a municipality located on the Restigouche River in the Gaspésie region of eastern Quebec, Canada.

It is about a half-mile west of Pleasant Loint, indicating a new border between land claimed by Isaac Mann and the newly surveyed Restigouche Indian Reserve.

The local Mi'kmaq had remained relatively isolated from intrusion except by the European fishermen and a few fur traders and missionaries.

The events leading up to the Battle of Restigouche were the beginning of a significant intrusion into the heart of Northern Mi'kmaq territory.

Many artefacts from a site in Restigouche-Sud Est have been discovered that may indicate a French establishment of the period (late 1600s).

During the Battle of Ristigouche an eyewitness description of the events of the third of July 1760 refers to a sort of village or group of Acadian dwellings numbering between 150 and 200, burned by the English.

The first large group had arrived in 1757 with Joseph Leblanc dit Le Maigre and had spent the first winter near the Sugarloaf Mountain but transferred across to the place referred to as La Petite Rochelle in spring of 1760.

Further upriver near Listuguj, the Battle of Restigouche ended with all the French ships and most of the Acadians' boats sunk, but the English were not successful in landing.

After the conquest, Pointe-à-la-Croix was primarily a fishing, forestry, and farming community until the opening of the J. C. Van Horne Bridge to Campbellton in 1962.