Pointe Mouillee State Game Area was established in 1945 and is administered by the Michigan Department of Natural Resources.

[3] Pointe Mouillee State Game Area is located in southeast Michigan around the mouth of the Huron River at Lake Erie.

The northern portion is mostly within Brownstown Charter Township along the Huron River with a small marshy area to the north near Milleville Beach.

Portions of the state game area and surrounding waters have been listed as a potential expansion to the Detroit River International Wildlife Refuge.

The project aimed to create an elongated and narrow barrier island (or dike) to control water levels within the marshlands and provide protection from erosion.

When the project was completed in 1981, the barrier island measured 3.5 miles (5.6 km) long, 1,400 feet (426.7 m) wide, and about 700 acres (2.8 km2) in size.

[10][11] In 1982, remaining dredged materials were no longer needed at Pointe Mouillee and were dumped at Grassy Island further north in the Detroit River.

The marsh gradually receded over the years as Lake Erie's fluctuating waters eroded the protective barrier islands.

In 1945 the Michigan Department of Conservation purchased the land with revenue from federal Pittman–Robertson excise taxes and the state Game and Fish Protection Fund.

Hiking and biking are common activities along the artificial dike and marshlands, although some places are designated wildlife areas with limited access.

Prohibited activities include camping, horseback riding, use of off-road or all-terrain vehicles, and trapping without written permission.

[16] While there are numerous shore fishing locations, the Michigan Department of Natural Resources maintains three boat launches within the game area.

The only launch with a paved ramp and direct access to Lake Erie is located at the Huron River mouth near the park's headquarters.

The most abundant bird species within the area include tundra swans, redheads, wood ducks, canvasbacks, gadwalls, American wigeons, mallards, blue-winged teals, lesser yellowlegs, and short-billed dowitchers.

[23] The American white pelican has also been spotted along the Detroit River and especially at Pointe Mouillee State Game Area.