[3] Pomaderris vacciniifolia was first formally described in 1858 by Siegfried Reissek in the journal Linnaea: Ein Journal für die Botanik in ihrem ganzen Umfange from specimens collected by Ferdinand von Mueller near Watts River.

[4] Round-leaf pomaderris grows in moist forest and scrub, mostly in the upper and middle catchments of the Yarra River between Healesville, Eltham and Flowerdale.

[2][3] Pomaderris vacciniifolia is classified as "critically endangered" under the Australian Government Environment Protection and Biodiversity Conservation Act 1999 and as "endangered" under the Victorian Government Flora and Fauna Guarantee Act 1988.

The main threats to the species include weed invasion, grazing by herbivores and road maintenance.

Factors in the decline of the species include browsing by feral deer, land clearing, and the 2009 Black Saturday bushfires.