Pontiac station is served by the Illinois-focused Lincoln Service between Chicago Union Station and the Gateway Transportation Center in St. Louis, Missouri and the long-distance Texas Eagle between Chicago and Los Angeles Union Station.

Until April 2007, Pontiac was also served by the Ann Rutledge, a train from Chicago to Kansas City Union Station.

The station also has a wheelchair lift and handicap-accessibility per the Americans with Disabilities Act of 1990.

Pontiac originated as a stop on the Chicago and Alton Railroad.

[5] An older depot, located one block north of the new station, is now a pizza restaurant.