The album utilises a straightforward format: all of Erasure's singles up to that point, sequenced in chronological order with the addition of the Hamburg Mix of Erasure's first ever single, "Who Needs Love (Like That)".

In the UK, "Who Needs Love Like That" was released as a single in remixed form ("The Hamburg Mix", a reference to Erasure's extensive touring of Hamburg during the band's formative period).

The First 20 Hits became Erasure's fourth consecutive number-one album in the UK.

The Second 20 Hits (direct sequel including the subsequent 20 singles sequenced chronologically) released 17 years later, and Total Pop!

All tracks are written by Clarke/Bell, except as indicated ^ Shipments figures based on certification alone.