2 May 1250–July 1250 AD: Shajar al-Durr (شجر الدر, "Tree of Pearls") whose Royal Name was al-Malika `Aṣmat ad-Dīn Umm-Khalīl Shajar ad-Durr (الملكة عصمة الدين أم خليل شجر الدر) (nicknamed: أم خليل, Umm Khalil; mother of Khalil) (died 28 April 1257 in Cairo).
Izz al-Din Aybak (عز الدين أيبك) was the first of the Mamluk sultans of Egypt in the Turkic Bahri line, if the reign of Shajar al-Durr is discounted.
24 October 1260 - 1 July 1277 AD: The Reign of Mamluk Sultan al-Zahir Rukn al-Din Baibars (Baybars) I al-Bunduqdari (1260-1277 AD, 658-665 AH, died in office)(الملك الظاهر ركن الدين بيبرس البندقداري) nicknamed Abu al-Futuh and Abu l-Futuhat (أبو الفتوح; "Father of Conquest", referring to his victories) — He was one of the commanders of the Muslim forces that defeated King Louis IX of France to end the Seventh Crusade (1248 to 1254).
Louis IX was defeated by the Ayyubid Sultan Al-Muazzam Turanshah, supported by Faris ad-Din Aktai's Bahariyya Mamluks, Baibars al-Bunduqdari, Qutuz, Aybak, and Al-Mansur Qalawun.
The reign of Baibars marked the start of the age of Mamluk dominance in the Eastern Mediterranean and solidified the durability of their military system.
However, when Sultan Ezzeddin Aybak ((الملك المعز عز الدين أيبك التركماني الجاشنكير)) became the de facto ruler in 1250 AD, the Copts offered him a gift of 500 dinars for the purpose of this ordination, and he accepted it.
His name was Paul ibn Kalil al-Masri (القس بولس الراهب الأنطوني المعروف بابن كليل المصري).
When he was chosen for the patriarchate, he was promoted to the rank of Hegumen ( درجة الإيغومانوسية) of the Hanging Church (الكنيسة المعلقة) in Cairo on Sunday 2 October 1250 AD (5 Baba 967 AM) with great glory and celebration.
After being promoted to the rank of Hegumen in Cairo, he traveled with the bishops, the senior clergy, and the Coptic leaders to Alexandria to complete his ordination as Patriarch, as was the custom.
At the time of the ordination of Pope Athanasius III, the Vizier Sharafuddin Abi Said the son of Sa'id al-Nayizi (الوزير شرف الدين أبي سعيد هبة الله بن صاعد النايزي) was present in Alexandria.
In the year 1257 AD (973 AM), Pope Athanasius III consecrated the Holy Oil of Chrismation (the Myron, الميرون) in the monastery of St Macarius (Abi Makar, دير أبي مقار).
When he became patriarch, he attempted everything within his power to heal the church and repair the damage caused by his predecessor, Cyril III (البابا كيرلس بن لقلق).
Following the Battle of Ain Jalut and the defeat of the Mongols, the Mamluk Sultan al-Malik al-Muzafar Seif al-Din Qutuz entered Damascus, and ordered the Christians to pay 150,000 Dirhams, which collected from them and carried to him by the Embassy of the Persian Prince Farisuddin Aktay (الأمير الفارسي فارس الدين أقطاي المستعرب أتابك المعسكر).