The curriculum at Pope John XXIII High School provides multiple pathways of academic function - College Preparatory, Honors and Advanced Placement.

Seniors Mike Thompson, Marquis Bouyer and Juniors Mekhi Collins, and Luis Velasquez started the game for the Tigers.

The 2018 Pope John Football team went undefeated in the Catholic Central (Small) League winning that championship.

In the MIAA playoffs, Pope John won the Eastern Massachusetts Championship before falling to Saint Bernard Catholic High School in the Super Bowl played at Gillette Stadium.

Extracurricular activities include campus ministry, drama and Theatre Arts, the school newspaper The Mercury, the chess club, and student government.