Regular cargo and passenger ferry lines connect to German and Swedish ports Kiel, Travemünde, Rostock, Karlshamn and Trelleborg.

Main deepsea container lines operating in Klaipėda port are: Maersk, MSC, CMA-CGM, Happag-Lloyd, One, Evergreen, OOCL, Cosco.

Klaipėda State Seaport Authority (Lithuanian: Klaipėdos valstybinio jūrų uosto direkcija) was established in 1991, soon after the restoration of Lithuania's independence.

The port is served by two railway stations and a highways which together link Klaipėda to Kaunas, Vilnius and cities in the nearby countries, such as Minsk, Kyiv and Moscow.

About 321,000 international passengers transhipped the port of Klaipėda in 2010, on ferries servicing Kiel and Mukran in Germany, Åhus in Sweden, and Copenhagen and Fredericia in Denmark.