Portageville is a city in New Madrid and Pemiscot counties in the U.S. state of Missouri.

"In 1935, the Portageville Pirates are awarded the second-half title after the Jackson Generals and Union City Greyhounds are disqualified for having too many class players on their rosters.

[citation needed] Portageville is located primarily in New Madrid County.

Portageville is about 5 miles (8.0 km) west of the Mississippi River.

According to the United States Census Bureau, the city has a total area of 2.04 square miles (5.28 km2), all land.

[8] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

29.8% of all households were made up of individuals, and 14.2% had someone living alone who was 65 years of age or older.

29.6% of all households were made up of individuals, and 15.1% had someone living alone who was 65 years of age or older.