Portet-sur-Garonne (French pronunciation: [pɔʁtɛ syʁ ɡaʁɔn], literally Portet on Garonne; Languedocien: Portèth de Garona) is a commune in the Haute-Garonne department in southwestern France.

Portet-Saint-Simon station has rail connections to Foix, Tarbes, and Toulouse, which is the nearest big city, about 10 km away.

The inhabitants of the commune are known as Portésiens in French.

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