Portrait of Isabel Rawsthorne Standing in a Street in Soho is a 1967 oil-on-canvas painting by the Irish-born English figurative artist Francis Bacon, housed in the Neue Nationalgalerie, Berlin.

Described by art critic John Russell as one of Bacon's finest works,[1] it depicts Isabel Rawsthorne, the painter, designer and occasional model for artists such as André Derain, Alberto Giacometti and Picasso.

According to his biographer Michael Peppiatt, "in her animal exuberance and the resolute sense of her individuality ... she had a magnetism and mobility of expression that captivated Bacon".

By this time he was highly social, and liked to spend long nights with associates such as Lucian Freud (they later fell out, for unexplained reasons), Peter O'Toole, George Melly, Muriel Belcher, John Deakin and Henrietta Moraes.

Belcher was a close friend, and the proprietor of the highly selective Colony Room in Dean Street, Soho.