Portrait of Lorenzo Cybo (1524) is a painting by the Italian late Renaissance artist Parmigianino.

The painting is mentioned by late Renaissance art biographer Giorgio Vasari as among those that Parmigianino executed during his sojourn in Rome.

The date 1523 is generally considered to be a mistake of the unknown man who added the inscription, since at the time Parmigianino was still in Emilia.

The portrait is known since 1749, when it was part of the collections of cardinal Silvio Valenti Gonzaga, and is in fact included in a painting depicting his pictures by Giovanni Paolo Pannini.

There are several known copies, including one at the Columbia University in New York City, which once belonged to countess Frenfanelli Cybo.