When the Ottomans had captured Constantinople in 1453, Pope Calixtus III issued a call to a Crusade, which was delivered to Afonso V of Portugal via the Bishop of Silves, and the king pledged to assemble an army to use against the Muslims.

[1] After Calixtus had died in 6 August 1458, Afonso decided to attack Tangier in Morocco instead, but was persuaded by the governor of Ceuta Count Sancho de Noronha to divert his forces to capture of Ksar es-Seghir instead, which the king accepted.

[2] Marinid rulers after 1420 came under the control of the Wattasids, who exercised a regency as Abd al-Haqq II became Sultan one year after his birth.

[1] Afonso V moved to Ceuta, and organized an embassy to deliver to the Sultan of Fez a "polite letter" challenging him to a pitched battle, however his ships were shot at upon sailing into the harbour of Tangier.

The mosque was transformed into a church under the invocation of Santa Maria da Misericórdia, granted to the Order of Christ on the initiative of Prince Henry.

[5] This event saw the end of the Marinid dynasty as Muhammad ibn Ali Amrani-Joutey, leader of the Sharifs, was proclaimed Sultan in Fes.