In the episode, Spike, Twilight Sparkle, Rainbow Dash, Fluttershy, Applejack, Rarity, and Pinkie Pie are transported into a comic book where they become its characters.
The episode was heavily influenced by comic books, including having a more modern and futuristic style.
In the comic, the ponies get transformed and assume the personas of the Power Ponies: Twilight Sparkle is transformed into Masked Matter-Horn, who can shoot power beams; Pinkie Pie into Fili-Second, who has super speed; Rainbow Dash into Zapp, who can control nature; Rarity into Radiance, who can create objects with her bracelets; Applejack into Mistress Mare-velous, who is psychically connected to her lasso; and Fluttershy into Saddle Rager, who turns into a monster when she loses her temper, while Spike is transformed into their bumbling sidekick, Hum Drum, to his annoyance.
As the Mane-iac threatens them with her doomsday weapon, which will cause every pony's hair to grow wild, Spike hides, feeling useless.
Fluttershy, reluctant to join the battle, turns to leave, but the Mane-iac spots her and tries to shoot her with a cannon.
Its perspective was harder than usual, with "strong parallaxes that show the dynamic viewpoint of comics.