[1] The band's history can be traced back to the 1990s, where the band members would often collaborate - such as Senen "Sen Dog" Reyes and Billy Biohazard performing on Biohazard's State Of The World Address album with the hit single How it is, or Wolbers and Lozano appearing in Cypress Hill albums Skull & Bones and Stoned Raiders.

In 2015, Roy Lozano played some demos to Senen Reyes on a ride to the airport, setting the foundations for Powerflo.

Describing their sound as a "cross between Iron Maiden, Black Sabbath and Cypress Hill", they first unveiled the band on March 1, 2017 while recording their self-titled debut album.

On June 2, 2017, Powerflo released their next music video (directed by Graziadei) for "Victims of Circumstance", a song influenced by the TV series The First 48.

Powerflo released the next video for "Less than Human" (directed by Graziadei) in December 2017 and went on tour with Prong in the spring of 2018.