Poydras is a census-designated place (CDP) in St. Bernard Parish, Louisiana, United States.

Poydras is on the East Bank of the Mississippi River, just upriver from the Plaquemines Parish line.

Albert Estopinal, Jr., a St. Bernard Parish district attorney, judge, and sheriff, was born in Poydras in 1869 to later U.S. Representative, Albert Estopinal, Sr.[2] The locally constructed levee failed during the 1922 flood and the community of Poydras was destroyed.

[3] The New Orleans river stage dropped .2 foot within 24 hours of the Poydras crevasse and a sound levee had been inspected and reported only 30 minutes before the breach occurred.

According to the 2020 United States census, there were 2,536 people, 944 households, and 638 families residing in the CDP.