Prairie City is an unincorporated community and census-designated place in Perkins County, South Dakota, United States.

[6] Moreover, both a railroad and a highway—which had initially been slated to pass through Strool—were later built several miles away, bypassing the area and making it inconvenient to reach.

[5][6] By 1946, some residents of Strool had decided to relocate two miles north and form the settlement of Prairie City.

[6] The move to Prairie City was hastened by multiple factors, including the arrival of electrical infrastructure in 1952 (as settlers did not want to install electricity in rented property), Ben Strool's death in 1949, and a subsequent feud over the ownership of the settlement.

At the 2010 United States census, there were 23 people, 9 households, and 4 families living in Prairie City.