Pramarn Adireksarn was born on 31 December 1913 in Saraburi to a Chinese immigrant father and Thai mother.

The 1957 military coup d'état by Field Marshal Sarit Thanarat deposed Pramarn's patron Plaek and brought his political career to a temporary halt.

[5] In 1974, after the successful democratic uprising, Pramarn, together with his in-laws Chatichai Choonhavan and Siri Siriyothin, founded the Thai Nation Party.

[7] In advance of the snap elections, Pramarn's Thai Nation Party campaigned on the slogan "Right kill Left".

This time, the Thai Nation Party joined a Democrat Party-led government under Kukrit's brother M.R.

This was eventually executed by the police and ultra-right paramilitary units who shot and struck at least 46 protesters at the Thammasat University dead.

[5] In January 1990 he switched posts with fellow party member Banharn Silpa-archa and took over the industry portfolio, just to change back to the interior ministry in December of the same year.

The so-called National Peace Keeping Council seized 139 million baht of Pramarn's assets, accusing him of being "unusually rich" for a cabinet member.