On 26 February 2022, the Ukrainian Chorus Dumka of New York performed the hymn in the cold open of Saturday Night Live.

Oleksandr Konysky wrote a patriotic poem from February to 28 March 1885 in Kyiv,[1][2] at a time when the Imperial Russian government suppressed the use of the Ukrainian language.

[2] On August 2, Prayer was first performed in Ternopil at a literary and musical evening on the occasion of a travel of Lviv students in Podillya.

[5] The Prayer became widespread in the beginning of the 20th century in arrangements for mixed choir made by Viktor Matiuk [uk] in 1907, and Kyrylo Stetsenko and Oleksandr Koshyts in the 1910s.

[1] It acquired symbolic significance during the Ukrainian War of Independence in 1917–1920, then performed by thousands of choirs, conducted by Kyrylo Stetsenko, on Bohdan Khmelnytsky Square in Kyiv.

[6][7] Боже великий, єдиний, Нам Україну храни, Волі і світу промінням Ти її осіни.

Молимось, Боже єдиний, Нам Україну храни, Всі свої ласки й щедроти Ти на люд наш зверни.

Molymoś, Bože jedynyj, Nam Ukrainu chrany, Vsi svoi lasky j ščedroty, Ty na liud naš zverny.

[21] It was performed on Khreshchatyk, the main street of Kyiv, in 2001 during the celebrations of the 10th anniversary of Ukraine's independence; The Ukrainian Weekly described it as "perhaps one of the most inspiring moments of the parade".

[33] On 24 February 2022, the day that the invasion officially began, the Los Angeles Chamber Orchestra spontaneously included "Prayer for Ukraine", arranged by its music librarian Serge Liberovsky, in a series concert in Santa Monica, between Mozart's Divertimento for String Trio and Dvořák's Serenade for Winds.

[3] On 26 February, the Ukrainian Chorus Dumka of New York, a group founded in 1949 "to preserve and cultivate the rich musical heritage of Ukraine",[34] performed the hymn in the cold open of Saturday Night Live, standing behind a table of candles that were arranged to spell "Kyiv".