Preah Sdach (Khmer: ព្រះស្ដេច, pronounced [prĕəh sɗac]; "Sacred Prince") is a district located in Prey Veng Province, in south eastern Cambodia.

The most popular market of Preah Sdach District is Phsar Trea which is located in Trea Commune.

The Japanese-Cambodian Friendship High School is also in this district.

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