The song has been performed by a wide variety of famous recording artists, including Tammy Wynette, Bill Monroe, Rosetta Tharpe, Johnny Cash, Willie Nelson, Alan Jackson, Emmylou Harris, Daniel O'Donnell, Gerry Rafferty, the Edwin Hawkins Singers, a duet by George Jones and Patti Page, Jim Reeves, Bob Dylan, Waylon Jennings, J. J. Cale, and James Blackwood's quartet.
Dolly Parton recorded the song on her 1999 Dollywood-exclusive album benefitting the Dollywood Foundation, Precious Memories.
A cover by The Stanley Brothers can be heard on Rick Grimes' (Andrew Lincoln) radio at the beginning of The Walking Dead fourth-season premiere episode, "30 Days Without An Accident".
Susan Raye's cover was in the opening and closing credits sequences of Paul Schrader's 1979 crime drama, Hardcore.
A version by Sister Rosetta Tharpe was played in the opening credits to the 1990 film To Sleep with Anger.