Presles-en-Brie (French pronunciation: [pʁɛl ɑ̃ bʁi] ⓘ, lit.

'Presles in Brie') is a commune in the Seine-et-Marne department in the Île-de-France region in north-central France.

The inhabitants are known as Preslois in French.

It is twinned with Wavendon, England.

This article related to a Seine-et-Marne location is a stub.